Sadly, using the Turkey Tail for my partner with active Prostate cancer did not have any effect in lowering his PSA or the size of the cancers on his bones. He felt no other benefits from using it at a high dosage as advised. I used the 6 Blend but don't seem to notice any change except perhaps a bit more clarity for organising busy days. I will stop taking it and see if I notice any difference. Great company and brilliant back up and support just sadly not what we were hoping for.